Problems in Public Distribution System

To minimize the poverty level among general public, Government of India promoted Public distribution system for extending basic necessary goods at subsidized rates. But their primary motto has not been fulfilled due to numerous problems prevailing in PDS. Thus, an attempt has been made in this study to ascertain the Problems prevailing in PDS. The result of the study indicates that Adulteration, Distribution of inferior quality goods, Under Weighment are the common problems found in Public distribution system

Phytochemical constituents of Cadaba Trifoliata Roxb. root extract

Cadaba trifoliata Roxb is belongs to the family Capparaceae, important medicinal plant of Indian medicinal plants. The methanol, ethanol, ethyl acetate and aqueous extracts along with dry powder of root were screened for the presence of phytochemicals. The phytochemical constituents were analyzed by qualitative and GC-MS method. Preliminary studies showed that the presence of Tannins, Steroids, Alkaloids, Glycosides, Flavonoids and Phenolic compounds. In the GC-MS analysis, 17 bioactive phytochemical compounds were identified in the alcoholic extract. The identification of phytochemical compounds in very high peak area, 1, 2-Benzenedicarboxylic acid, diisooctyl ester (C24H38O4) with RT 24.95 has peak area 51.86% and 1-Methyl-pyrrolidine-2-carboxylic acid (C6H11NO2) with RT 6.89 has peak area 20.58%. The main important compound phytol (C20H40O) with RT 18.95 ranks with peak area 1.21%. A nature compound contains diterpene activity anti-cancer, anti-diabetic, anti-inflammatory, anti-oxidant activity and antimicrobial activity.Keywords:- Cadaba trifoliata, phytochemical constituents, alcoholic root extracts

Tris(2,4-di-tert-butyl­phen­yl) phosphate

The title compound, C42H63O4P, was isolated from the leaves of Vitex negundo. Two of the tert-butyl groups are disordered over two orientations with occupancy ratios of 0.57 (1):0.43 (1) and 0.67 (1):0.33 (1). Several intra­molecular C—H⋯O inter­actions are observed in the mol­ecular structure

1-Methyl-3-(2-methyl­phen­yl)-3a-nitro-1,2,3,3a,4,9b-hexa­hydro­chromeno[4,3-b]pyrrole

The asymmetric unit of the title compound, C19H20N2O3, contains two independent mol­ecules in both of which the pyrrolidine ring adopts an envelope conformation, but with a C atom as the flap in one mol­ecule and the N atom in the other. The pyran ring adopts a half-chair conformation in both mol­ecules. In the crystal, mol­ecules are linked via C—H⋯O hydrogen bonds and C—H⋯π inter­actions

1-(2-Azido­acet­yl)-3-methyl-2,6-diphenyl­piperidin-4-one

In the title compound, C20H20N4O2, the piperidine ring adopts a distorted boat conformation. The two phenyl rings form dihedral angles of 82.87 (1) and 84.40 (1)° with respect to the piperidine ring. The crystal packing is stabilized by inter­molecular C—H⋯O and C—H⋯N inter­actions

A Role of Knowledge Level of Employees in Customer Relationship Management With Special Reference to Lic

Purpose: Role ofknowledge level of employees in customer relationship management with special reference to LIC. In order to investigate a range of factors of CRM in LIC of India. In this specially concentrate to understand the knowledge level of the employees as perceived by the customer.   Theoretical framework: The theoretical frame work of the study, CRM is assessed the Knowledge level of employees isthe independent variables and the customer satisfaction is the dependent variable in the study. CRM is shown influencing the customer satisfaction. The significant influences of the factors on CRM vary according to different demographic profiles and views on policy holdings.   Design/Methodology/Approach:Descriptive research design was use in this studyThe prime data were collected from the sample of the respondents was identified from the total population of lic policy holders. The statistical analysis was carried out with the application of SPSS package. Both Descriptive and Inferential Analysis were carried out. The tools for the Inferential Analysis included Independent Sample t-test, One Way ANOVA, Chi Square Test, Friedman Test, Correlation and Regression.   Findings: The findings of the study based on output of the study. Henceforth reasoned that there is a huge distinction between mean positions towards Factors of Customer Relationship Management. In light of mean position, Customer Engagement is the main variable of CRM, trailed by Deployment of Modern Technology Knowledge level of the Employees etc. There is no importance contrast between capability of representatives concerning the Factors of Knowledge level of the Employees, There is significance contrast among male and female of laborers with respect to the Factors of Knowledge level of the Employees. The connection coefficient between Perception on Explanation of various items and Ready for Clarification is positive connections between Perception on Explanation of various item and Perception on Ready for Clarification .The connection coefficient between Explanation of various item and Recommending Right Schemes is positive connections between Explanation of various item and Recommending Right Schemes. The connection coefficient between Perception on Explanation of various items and Knowledge about Procedure is positive connections between Perception on Explanation of various items and Easy Acquisition of Policy and also different variables are decidedly corresponded with one another.   Research, practical & social implications:This article express a different perspective on CRM in LIC.The results of this study indicate knowledge level of employees has a strong impact on customer satisfaction. Therefore top management should implement latest technology based increase the knowledge level of employees. To increase the knowledge level of employees to help the increasing satisfaction level of policy holders. It is intended to help guide and reassure current and potential Ph. D students.   Originality/value:To date, no systematic review has been conducted on the knowledge level of employees in LIC .This paper makes an important contribution to knowledge level of employees in CRM

3′-Hy­droxy­methyl-1′-methyl-3′-nitro-4′-(o-tol­yl)spiro­[indoline-3,2′-pyrrolidin]-2-one

The title compound, C20H21N3O4, crystallizes with two mol­ecules in the asymmetric unit. In both mol­ecules, the pyrrolidine ring adopts an envelope conformation. The crystal structure is stabilized by inter­molecular C—H⋯O, N—H⋯O and O—H⋯O hydrogen bonds

TENSILE TEST ANALYSIS OF NATURAL FIBER REINFORCED COMPOSITE

This project mainly deals with analysis of tensile properties of Palmyra fiber Reinforced Epoxy Composite that is suitable for automobile application. First, the property of material was obtained on the basis of some assumptions (i.e., Rule of Mixture) and was modeled with reference to ASTM D638. Here the simulation was carried out on specimen under different fiber volume fraction and fiber length. The present work includes the Analysis of Palmyra Fiber Reinforced Epoxy Composites using FEA with various fiber volume fractions and these results were validated with the experimental result. The tensile property of Palmyra fiber composite material can be obtained by using tensometer.During the tensile load, the maximum strain, stress and displacement were obtained and, then this experimental result was compared with the analytical results and the error percentage of these results were calculated

Molecular Modeling Studies and ADME Screening on HIV-1 Integrase Inhibitors as Anti-Viral Agents

Abstract: Human immunodeficiency virus (HIV) is a lentivirus, a member of the retrovirus family, which leads to acquired immunodeficiency syndrome (AIDS). HIV is present as both free virus particles and virus within infected immune cells. Integration of viral DNA into the host chromosome is the key process in the HIV replication cycle and therefore Integrase has served as an attractive target for antivirals. HIV-1 Integrase (HIV-1 IN) is an essential enzyme in the life cycle of the virus, responsible for catalyzing the insertion of the viral genome into the host cell chromosome and it provides an attractive target for antiviral drug design. Antiretroviral treatment reduces both the mortality and the morbidity of HIV infection. Raltegravir, also known as Isentress and MK-0518, is a well known integrase inhibitor. This prevents the virus from making new copies of HIV. Structures similar to this compound were identified and molecular modeling studies has been performed with HIV-1 IN as target molecule using Schrödinger Suite 2007. PASS (prediction of activity spectra for substances) prediction of the compounds was carried out and all compounds exhibited anti-viral activity. These compounds show favorable interactions with the amino acid residues and the metal ion (Mg 2+ ) at the active site of HIV-1 IN thereby substantiating their proven efficacy as anti-viral compounds. Further, their ADME (Absorption, Digestion, Metabolism and Excretion) screening was also carried out in order to check their potency to be used for second-generation drug development. The work demonstrates that molecular modeling, activity prediction and screening of the compounds for their subsequent ADME properties is a promising approach to predict the binding activity of compounds to the receptor